Rat TNF alpha ELISA Kit

Catalog No.: IRKTAH5540


Category: Assay and ELISA Kits

  • Description

  • SDS

  • Sample Datasheet

  • Info Request

Product Description

Rat TNF alpha ELISA Kit - 1 Kit (96 Wells)

Our Rat TNF alpha ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat TNF alpha in cell culture supernates, serum and plasma (heparin, EDTA).

Tumor necrosis factor-alpha(TNF-alpha, or TNF) is secreted by macrophages in response to inflammation, infection and cancer. Human Tumor Necrosis Factor(TNF) and Lymphotoxin(TNF-beta) are cytotoxic proteins which have similar biological activities and share 30% amino acid homology. TNF-alpha is produced by monocytes, which can stimulate endothelial cells to produce the multilineage growth factor granulocyte-macrophage colony-stimulating factor and extend the role of this immunoregulatory protein to the regulation of hematopoiesis in vitro. TNF is a soluble protein that causes damage to tumor cells but has no effect on normal cells. Human TNF has been purified to apparent homogeneity as a 17.3-kilodalton protein from HL-60 leukemia cells and has showed cytotoxic and cytostatic activities against various human tumor cell lines. The human TNF cDNA is 1585 base pairs in length and encodes a protein of 233 amino acids. The mature protein begins at residue 77, leaving a long leader sequence of 76 amino acids. TNF-alpha has been mapped to human chromosome 6. The standard product used in this kit is recombinant rat TNFalpha, consisting of 157 amino acids with the molecular mass of 17KDa.

Contact Us About This Product

Rat TNF alpha ELISA Kit

© 2018 Innovative Research. All Rights Reserved.