Rat IL-13 ELISA Kit - 1 Kit (96 Wells)Our Rat IL-13 ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat IL-13 in cell culture supernates, serum and plasma (heparin, EDTA).
Interleukin 13(IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2(Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor(IL-4Ralpha) and at least one of two known IL-13-specific binding chains. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, signal transducer and activator of transcription 6(STAT6). The IL13 gene is clustered with IL3, IL5, IL4, and CSF2 on 5q. Physical maps of the 5q23-q31 region show the following order: cen-IL3-CSF2-IL13-IL4-IL5-tel, with IL13 particularly close to IL4.