Mouse VCAM-1 ELISA Kit

Catalog No.: IRKTAH5475


Category: Assay and ELISA Kits

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Product Description

Mouse VCAM-1 ELISA Kit - 1 Kit (96 Wells)

Our Mouse VCAM-1 ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse VCAM-1 in cell culture supernates, serum and plasma (heparin, EDTA).

Vascular cell adhesion molecule 1(VCAM-1) is a cell surface glycoprotein adhesive for certain blood leukocytes and tumor cells, which is expressed by activated endothelium in a variety of pathologic conditions including atherosclerosis.Increased expression of VCAM1 is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention.Integrin alpha4beta1(VLA-4) and VCAM-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization.The VCAM1 gene is assigned to the 1p31-32 region of chromosome 1 based on the analysis of human-mouse hybrid cell lines and in situ hybridization.The standard product used in this kit is recombinant mouse VCAM-1, a dimeric protein linking with a disulfide bond. It consists of Phe25-Glu698 amino acid sequence of a single chain with the molecular mass of 101.9KDa. As a result of glycosylation, the molecular mass of 120KDa is revealed by SDS-PAGE.

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Mouse VCAM-1 ELISA Kit

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