Mouse TFPI ELISA Kit - 1 Kit (96 Wells)Our Mouse TFPI ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse TFPI in cell culture supernates, serum and plasma (heparin, EDTA).
TFPI(Tissue factor pathway inhibitor),also known as EPI, LACI or TFPI1, is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. TFPI consists of a highly negatively-charged amino-terminus, three tandemly-linked Kunitz domains, and a highly positively-charged carboxy-terminus. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.