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ELISA Kit

Mouse Neprilysin/CD10 ELISA Kit

Catalog No.: IRKTAH5420

$495

Category: Assay and ELISA Kits

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Product Description

Mouse Neprilysin/CD10 ELISA Kit - 1 Kit (96 Wells)

Our Mouse Neprilysin/CD10 ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse CD10 in cell culture supernates, serum and plasma (heparin, EDTA).

Neprilysin, also known as membrane metallo-endopeptidase, neutral endopeptidase(NEP), CD10, and common acute lymphoblastic leukemia antigen(CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease, this gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, Neprilysin is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. Neprilysin has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.

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Mouse Neprilysin/CD10 ELISA Kit

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