Mouse IL15RA ELISA Kit

Catalog No.: IRKTAH5381


Category: Assay and ELISA Kits

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Product Description

Mouse IL15RA ELISA Kit - 1 Kit (96 Wells)

Our Mouse IL15RA ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse IL15RA in cell culture supernates, serum and plasma (heparin, EDTA).

Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor which is encoded by the gene IL15RA in humans. The human IL15RA gene was mapped to chromosome 10p15-p14 by FISH and the mouse Il15ra gene was mapped to chromosome 2. The cytoplasmic domain of IL15R-alpha, like that of IL2R-alpha, was dispensable for mitogenic signaling, suggesting that the primary role of the alpha chains is to confer high-affinity binding. At high concentrations, IL15, like IL2, was able to signal through a complex of IL2R-beta and -gamma in the absence of the alpha subunit. The soluble receptor displayed high affinity for IL15 and inhibited both binding of IL15 to the membrane receptor and IL15-induced cell proliferation.

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Mouse IL15RA ELISA Kit

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