Mouse IL-33 ELISA Kit

Catalog No.: IRKTAH5395


Category: Assay and ELISA Kits

  • Description

  • SDS

  • Sample Datasheet

  • Info Request

Product Description

Mouse IL-33 ELISA Kit - 1 Kit (96 Wells)

Our Mouse IL-33 ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse IL-33 in cell culture supernates, serum and plasma (heparin, EDTA).

Interleukin 33(IL-33) is a cytokine belonging to the IL-1 superfamily. By genomic sequence analysis, the IL33 gene is mapped to chromosome 9p24.1 and its mouse homolog to a syntenic region on chromosome 19qC1. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 T cell(CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.

Contact Us About This Product

Mouse IL-33 ELISA Kit

© 2019 Innovative Research. All Rights Reserved.