Mouse Gp130/IL6ST ELISA Kit - 1 Kit (96 Wells)Our Mouse Gp130/IL6ST ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse Gp130 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
GP130(Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane protein which is the founding member of the class of all cytokine receptors. The GP130 gene is mapped on 5q11.2. Gp130 showed an apparent molecular mass of 130 kD by SDS-PAGE. Gp130 is involved in the formation of high-affinity IL6-binding sites and in IL6 signal transduction. Sgp130 has a role in modulating signals transduced by membrane-bound gp130. Gp130 is an important part of many different types of signaling complexes.Gp130 molecules with mutations in either of these segments could not transduce a growth signal.