Human sL-Selectin ELISA Kit

Catalog No.: IRKTAH5232


Category: Assay and ELISA Kits

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Product Description

Human sL-Selectin ELISA Kit - 1 Kit (96 Wells)

Our Human sL-Selectin ELISA Kit is a sandwich ELISA intended for the quantitative determination of human L-Selectin in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL(L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

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Human sL-Selectin ELISA Kit

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