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ELISA Kit

Human TNFRSF9/4-1BB ELISA Kit

Catalog No.: IRKTAH5273

$495

Category: Assay and ELISA Kits

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Product Description

Human TNFRSF9/4-1BB ELISA Kit - 1 Kit (96 Wells)

Our Human TNFRSF9/4-1BB ELISA Kit is a sandwich ELISA intended for the quantitative determination of human TNFRSF9 in cell culture supernates, serum and plasma (heparin, EDTA).

CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

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Human TNFRSF9/4-1BB ELISA Kit

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