x
ELISA Kit

Human TGFBR2 ELISA Kit

Catalog No.: IRKTAH5253

$495

Category: Assay and ELISA Kits

  • Description

  • SDS

  • Sample Datasheet

  • Info Request

Product Description

Human TGFBR2 ELISA Kit - 1 Kit (96 Wells)

Our Human TGFBR2 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human TGFBR2 in cell culture supernates, serum and plasma (heparin, EDTA).

TGFBR2(transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been characterized. TGFBR2 may be a target of the EWS-FLI1 fusion protein found in Ewing sarcoma and related peripheral primitive neuroectodermal tumors.

Contact Us About This Product

Human TGFBR2 ELISA Kit

© 2018 Innovative Research. All Rights Reserved.