Human TGFBI/beta IG-H3 ELISA Kit - 1 Kit (96 Wells)Our Human TGFBI/beta IG-H3 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human TGFBI in cell culture supernates, serum and plasma (heparin, EDTA).
Transforming growth factor, beta-induced, 68kDa, also known as TGFBI(initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.