Human REG-4 ELISA Kit - 1 Kit (96 Wells)Our Human REG-4 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human REG-4 in cell culture supernates, serum and plasma (heparin).
Regenerating islet-derived protein 4 is a protein that in humans is encoded by the REG4 gene. It is mapped to 1p12. REG-4 gene contains 6 exons and that the exon structure is preserved among members of the REG gene family. This gene is able to maintain carbohydrate recognition activity in an acidic environment. REG-4 expression was significantly upregulated by inflammation and tissue injury associated with active Crohn disease and ulcerative colitis, and most of the colorectal tumors overexpressing REG-4 are mucinous tumors or neuroendocrine tumors.