Human Periostin/OSF2 ELISA Kit - 1 Kit (96 Wells)Our Human Periostin/OSF2 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human Periostin in cell culture supernates, serum and plasma (heparin, EDTA).
Periostin, also known as OSF2, is a protein that in humans is encoded by the POSTN gene. The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells. It is found that periostin was overexpressed by the majority of human primary breast cancers examined. After myocardial infarction, periostin-induced cardiomyocyte cell cycle reentry and mitosis were associated with improved ventricular remodeling and myocardial function, reduced fibrosis and infarct size, and increase angiogenesis.