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ELISA Kit

Human MICB ELISA Kit

Catalog No.: IRKTAH5182

$525

Category: Assay and ELISA Kits

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Product Description

Human MICB ELISA Kit - 1 Kit (96 Wells)

Our Human MICB ELISA Kit is a sandwich ELISA intended for the quantitative determination of human MICB in cell culture supernates, serum and plasma (heparin, EDTA) .

MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer(NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis.

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Human MICB ELISA Kit

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