Human Kininogen-1/KNG1 ELISA Kit

Catalog No.: IRKTAH5165


Category: Assay and ELISA Kits

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Product Description

Human Kininogen-1/KNG1 ELISA Kit - 1 Kit (96 Wells)

Our Human Kininogen-1/KNG1 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human Kininogen-1 in cell culture supernates, serum and plasma (heparin, EDTA).

Kininogen-1 (KNG1), also known as alpha-2-thiol proteinase inhibitor, Williams-Fitzgerald-Flaujeac factor or the HMWK-kallikrein factor, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins high molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.

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Human Kininogen-1/KNG1 ELISA Kit

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