Human KLK1 ELISA Kit - 1 Kit (96 Wells)Our Human KLK1 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human KLK1 in cell culture supernates, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA).
Kallikrein-1, also known as tissue kallikrein, is a protein that in humans is encoded by the KLK1 gene. This serine protease generates Lys-bradykinin by specific proteolysis of kininogen-1. KLK1 is a member of the peptidase S1 family. Its gene is mapped to 19q13.3. In all, it has got 262-amino acids which contain a putative signal peptide, followed by a short activating peptide and the protease domain. The protein is mainly found in kidney, pancreas, and salivary gland, showing a unique pattern of tissue-specific expression relative to other members of the family. KLK1 is implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.