Human ICAM-3 ELISA Kit - 1 Kit (96 Wells)Our Human ICAM-3 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human ICAM-3 in cell culture supernates, serum and plasma (heparin, EDTA).
Intercellular adhesion molecule 3(ICAM3) also known as CD50(Cluster of Differentiation 50), is a human gene. The protein encoded by this gene is a member of the intercellular adhesion molecule(ICAM) family. ICAM3 is closely related to ICAM1, consists of 5 immunoglobulin domains, and binds LFA1 through its 2 N-terminal domains. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM3 has been shown to interact with EZR and Moesin.