Human Granzyme B ELISA Kit - 1 Kit (96 Wells)Our Human Granzyme B ELISA Kit is a sandwich ELISA intended for the quantitative determination of human Granzyme B in cell culture supernates, serum and plasma (heparin, EDTA).
Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes(CTL) and natural killer(NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.