Human Gp130/IL6ST ELISA Kit - 1 Kit (96 Wells)Our Human Gp130/IL6ST ELISA Kit is a sandwich ELISA intended for the quantitative determination of human soluble GP130 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
GP130(Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane proteinwhich is the founding member of the class of allcytokine receptors. The GP130 gene is mapped on 5q11.2. Gp130 showed an apparent molecular mass of 130 kD by SDS-PAGE. Gp130is involved in the formation of high-affinity IL6-binding sites and in IL6 signal transduction. Sgp130 has a role in modulating signals transduced by membrane-boundgp130. Gp130 is an important part of many different types of signaling complexes. Gp130 molecules with mutations in either of these segments could not transduce a growth signal.