Human Betacellulin/BTC ELISA Kit - 1 Kit (96 Wells)Our Human Betacellulin/BTC ELISA Kit is a sandwich ELISA intended for the quantitative determination of human Betacellulin in cell culture supernates, serum and plasma (heparin, EDTA).
Betacellulin, also known as BTC is a protein that in humans is encoded by the BTC gene. This gene is mapped to 4q13.3. The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. It is the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. This protein is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.