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ELISA Kit

Human ALCAM ELISA Kit

Catalog No.: IRKTAH5007

$495

Category: Assay and ELISA Kits

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Product Description

Human ALCAM ELISA Kit - 1 Kit (96 Wells)

Our Human ALCAM ELISA Kit is a sandwich ELISA intended for the quantitative determination of human ALCAM in cell culture supernates, serum and plasma (heparin , EDTA).

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The gene was mapped to human chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166(cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6 cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.

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Human ALCAM ELISA Kit

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