Non Swiss Albino Mouse Serum Reference 11-28-13
A quantitative LCMS/MS method for determination of thiazolidinedione mitoNEET ligand NL-1 in mouse serum suitable for pharmacokinetic studiesKK Pedada, X Zhou, H Jogiraju, RT Carroll - of Chromatography B, 2014 - Elsevier
Thiazolidinedione (TZD) compounds have shown promise as antidiabetic, antibiotics, antifungal and neuroprotective agents. The mitochondrial effect of a novel mitoNEET ligand, NL-1 5-(3,5-di-tert-butyl-4-hydroxyphenyl)methyl-1,3-thiazolidine-2,4-dione, and other TZD compounds, is a newly proposed mechanism for the neuroprotective action of these TZD compounds. In this work, a sensitive LCMS/MS assay has been developed and validated for quantification of NL-1 in mouse serum (Innovative Research, Novi, MI, USA)...