Prekallikrein Deficient Products

Prekallikrein Genetically Deficient (Knockout) Products are applicable to a wide range of in vitro research applications (including ELISA and Western Blot) and for many different areas of research, including coagulation and fibrionlysis. 

Our Prekallikrein Knockout was created by targeted disruption of the KLKB1 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. These knockouts demonstrate a complete absence of Plasma Kalikrein B Protein in plasma as confirmed by Western Blot, with greatly extended clotting time.

Products available include genetically deficient plasma, organs (flash-frozen), lyophilized organ powders, and ready-to-use organ tissue lysates. These products are ideal for use as standards or controls, including use as a negative control. 

We also offer Knockout Mice, available as individual male and/or female mice as well as breeding pairs. These Research Models are fully licensed and maintained as live colonies with immediate availability. Contact us directly for more information about live Research Models.