{"title":"Genetically Deficient Mouse Tissue Lysates","description":"\u003cp\u003e\u003cspan\u003eWe offer a line of genetically deficient mouse tissue lysates, collected from Research Models \u003c\/span\u003e\u003cspan\u003ewith\u003c\/span\u003e\u003cspan\u003e targeted disruption of the gene of interest. These products are ideal for use as highly-specific standards and controls, including as a negative control, since the protein of interest is genetically knocked out. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eWe offer Knockout Mice, available as individual male and\/or female mice as well as breeding pairs. These Research Models are fully licensed and maintained as live colonies with immediate availability. \u003ca href=\"https:\/\/www.innov-research.com\/pages\/contact-us\"\u003eContact us directly\u003c\/a\u003e for more information about live Research Models.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eAt Innovative Research, we are committed to providing reliable, consistent products that deliver reliable, consistent results. \u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-brain-tissue-lysate","title":"Mouse C1 Inhibitor Genetically Deficient Brain Tissue Lysate","description":"Mouse C1 Inhibitor Genetically Deficient Brain Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169122384,"sku":"IMSC1INHGDBRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_351f0620-cd37-493b-83b3-ad7cb6b892dc.png?v=1740405046"},{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-heart-tissue-lysate","title":"Mouse C1 Inhibitor Genetically Deficient Heart Tissue Lysate","description":"Mouse C1 Inhibitor Genetically Deficient Heart Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169155152,"sku":"IMSC1INHGDHTTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_5b793143-6888-434d-82db-2a6ccc133ca9.png?v=1740405048"},{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-kidney-tissue-lysate","title":"Mouse C1 Inhibitor Genetically Deficient Kidney Tissue Lysate","description":"Mouse C1 Inhibitor Genetically Deficient Kidney Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169187920,"sku":"IMSC1INHGDKDTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_12d61bf3-a3b0-40ea-8793-f31ca8fd1437.png?v=1740405048"},{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-liver-tissue-lysate","title":"*Mouse C1 Inhibitor Genetically Deficient Liver Tissue Lysate","description":"Select this product for Molecular Innovations name, Mouse C1 Inhibitor genetically deficient liver and product number, MC1INH-KO-LR.Mouse C1 Inhibitor Genetically Deficient Liver Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169384528,"sku":"IMSC1INHGDLRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_b026ccf0-ab5d-4cb9-a3f1-a4739b2b6890.png?v=1740405049"},{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-lung-tissue-lysate","title":"Mouse C1 Inhibitor Genetically Deficient Lung Tissue Lysate","description":"Mouse C1 Inhibitor Genetically Deficient Lung Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169548368,"sku":"IMSC1INHGDLGTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_b484fb42-d385-4744-9c47-ad28a8ec9728.png?v=1740405050"},{"product_id":"mouse-c1-inhibitor-homozygous-genetically-deficient-spleen-tissue-lysate","title":"Mouse C1 Inhibitor Genetically Deficient Spleen Tissue Lysate","description":"Mouse C1 Inhibitor Genetically Deficient Spleen Tissue Lysate from Innovative Research is prepared from a C1 Inhibitor Homozygous Knockout Mouse. This C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene. Homozygous mice completely lack C1 Inhibitor protein expression. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:C1 Inhibitor Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. Mouse Model Details Strain:C57BL6\/SJL Chromosome:2 Gene:SERPING1 Genomic TargetIntron 1, Exon 8 Mutation:9244 base pair deletion Phenotype:Absence of C1 Inhibitor protein expression and increased vascular permeability At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415169613904,"sku":"IMSC1INHGDSPTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_208ffb21-13f8-49d6-a16f-967054214796.png?v=1740405051"},{"product_id":"mouse-factor-ix-genetically-deficient-kidney-tissue-lysate","title":"Mouse Factor IX Genetically Deficient Kidney Tissue Lysate","description":"Mouse Factor IX Genetically Deficient Kidney Tissue Lysate from Innovative Research is prepared from a Factor IX knockout mouse. This Factor IX Knockout was created by targeted disruption of the F9 gene. Mutations were then confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor IX Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like coagulation and fibrinolysis. Factor IX deficiency is an animal model for Hemophilia B (Christmas Disease). Mouse Model Details Strain:C57BL6\/SJL Chromosome:X Gene:F9 Genomic TargetExon 1 Mutation:2 base pair deletion Phenotype:Prolonged clotting time (aPTT) and tail clipping-induced mortality. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415170859088,"sku":"IMSFIXGDKDTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_2f7918ed-ac6a-4f3f-bae4-52eeda139679.png?v=1740405053"},{"product_id":"mouse-factor-ix-genetically-deficient-liver-tissue-lysate","title":"Mouse Factor IX Genetically Deficient Liver Tissue Lysate","description":"Mouse Factor IX Genetically Deficient Liver Tissue Lysate from Innovative Research is prepared from a Factor IX knockout mouse. This Factor IX Knockout was created by targeted disruption of the F9 gene. Mutations were then confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor IX Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like coagulation and fibrinolysis. Factor IX deficiency is an animal model for Hemophilia B (Christmas Disease). Mouse Model Details Strain:C57BL6\/SJL Chromosome:X Gene:F9 Genomic TargetExon 1 Mutation:2 base pair deletion Phenotype:Prolonged clotting time (aPTT) and tail clipping-induced mortality. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415170924624,"sku":"IMSFIXGDLRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_585ccf80-d85c-458f-b580-e54f7e7a7b0c.png?v=1740405054"},{"product_id":"mouse-factor-ix-genetically-deficient-lung-tissue-lysate","title":"Mouse Factor IX Genetically Deficient Lung Tissue Lysate","description":"Mouse Factor IX Genetically Deficient Lung Tissue Lysate from Innovative Research is prepared from a Factor IX knockout mouse. This Factor IX Knockout was created by targeted disruption of the F9 gene. Mutations were then confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor IX Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like coagulation and fibrinolysis. Factor IX deficiency is an animal model for Hemophilia B (Christmas Disease). Mouse Model Details Strain:C57BL6\/SJL Chromosome:X Gene:F9 Genomic TargetExon 1 Mutation:2 base pair deletion Phenotype:Prolonged clotting time (aPTT) and tail clipping-induced mortality. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415171154000,"sku":"IMSFIXGDLGTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_ce0c80bc-d0e6-46bf-a41f-7b05519099b9.png?v=1740405055"},{"product_id":"mouse-factor-ix-genetically-deficient-spleen-tissue-lysate","title":"Mouse Factor IX Genetically Deficient Spleen Tissue Lysate","description":"Mouse Factor IX Genetically Deficient Spleen Tissue Lysate from Innovative Research is prepared from a Factor IX knockout mouse. This Factor IX Knockout was created by targeted disruption of the F9 gene. Mutations were then confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor IX Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like coagulation and fibrinolysis. Factor IX deficiency is an animal model for Hemophilia B (Christmas Disease). Mouse Model Details Strain:C57BL6\/SJL Chromosome:X Gene:F9 Genomic TargetExon 1 Mutation:2 base pair deletion Phenotype:Prolonged clotting time (aPTT) and tail clipping-induced mortality. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415171186768,"sku":"IMSFIXGDSPTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_1864c67d-d8c5-4f43-8ad3-8ce1d6b028f2.png?v=1740405056"},{"product_id":"mouse-factor-xii-genetically-deficient-brain-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Brain Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Brain Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173414992,"sku":"IMSFXIIGDBRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_e281eb5b-1692-48bc-b107-9480d7dcae11.png?v=1740405058"},{"product_id":"mouse-factor-xii-genetically-deficient-heart-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Heart Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Heart Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173480528,"sku":"IMSFXIIGDHTTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_111e892e-5f3c-480b-8148-6ab68d8d903e.png?v=1740405058"},{"product_id":"mouse-factor-xii-genetically-deficient-kidney-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Kidney Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Kidney Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173578832,"sku":"IMSFXIIGDKDTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_146184f1-c286-4cb0-a7df-9802759888f7.png?v=1740405059"},{"product_id":"mouse-factor-xii-genetically-deficient-liver-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Liver Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Liver Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173644368,"sku":"IMSFXIIGDLRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_946ec57b-6d91-4f91-aafc-ea4bdb14e854.png?v=1740405059"},{"product_id":"mouse-factor-xii-genetically-deficient-lung-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Lung Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Lung Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173709904,"sku":"IMSFXIIGDLGTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_bef59884-0783-4ae9-b51b-23e1bdc6b7a8.png?v=1740405060"},{"product_id":"mouse-factor-xii-genetically-deficient-spleen-tissue-lysate","title":"Mouse Factor XII Genetically Deficient Spleen Tissue Lysate","description":"Mouse Factor XII Genetically Deficient Spleen Tissue Lysate from Innovative Research is prepared from a Factor XII knockout mouse. This Factor XII Knockout was created by targeted disruption of the F12 gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:Factor XII Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in areas like cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:13 Gene:F12 Genomic TargetExon 8-12 Mutation:Large deletions Phenotype:Complete absence of FXII in plasma as confirmed by Western Blot. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415173742672,"sku":"IMSFXIIGDSPTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_6ab9f696-899b-49fa-975c-be7bf06c6d0e.png?v=1740405061"},{"product_id":"mouse-tpa-genetically-deficient-brain-tissue-lysate","title":"Mouse tPA Genetically Deficient Brain Tissue Lysate","description":"Mouse tPA Genetically Deficient Brain Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415178985552,"sku":"IMSTPAGDBRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_64fc4bb4-7fde-4af9-8680-1cb5b15b5063.png?v=1740405078"},{"product_id":"mouse-tpa-genetically-deficient-heart-tissue-lysate","title":"Mouse tPA Genetically Deficient Heart Tissue Lysate","description":"Mouse tPA Genetically Deficient Heart Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415179083856,"sku":"IMSTPAGDHTTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_8962d804-2f37-4217-9373-c05e90b3bbd7.png?v=1740405078"},{"product_id":"mouse-tpa-genetically-deficient-kidney-tissue-lysate","title":"Mouse tPA Genetically Deficient Kidney Tissue Lysate","description":"Mouse tPA Genetically Deficient Kidney Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415179116624,"sku":"IMSTPAGDKDTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_7582216e-37c2-413a-a2e3-6b97b6383605.png?v=1740405079"},{"product_id":"mouse-tpa-genetically-deficient-liver-tissue-lysate","title":"Mouse tPA Genetically Deficient Liver Tissue Lysate","description":"Mouse tPA Genetically Deficient Liver Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415179149392,"sku":"IMSTPAGDLRTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_3d4b269e-4315-427d-9945-7b28658b44e7.png?v=1740405080"},{"product_id":"mouse-tpa-genetically-deficient-lung-tissue-lysate","title":"Mouse tPA Genetically Deficient Lung Tissue Lysate","description":"Mouse tPA Genetically Deficient Lung Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"100ug","offer_id":31415179214928,"sku":"IMSTPAGDLGTL100UG","price":462.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/KnockoutMouse_3f9e7284-861f-4cc0-9bf6-d7450af566bb.png?v=1740405081"},{"product_id":"mouse-tpa-genetically-deficient-spleen-tissue-lysate","title":"Mouse tPA Genetically Deficient Spleen Tissue Lysate","description":"Mouse tPA Genetically Deficient Spleen Tissue Lysate from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal and stored frozen until lysed. The tissue is then lyophilized and thorougly homogenized in Radio Immuno Precipitation Assay (RIPA) buffer containing protease and phosphate incubators. The final homogenate is then incubated with DNase, clarified via centrifugation (10,000g at 4░C) and stored at -80░C. Each lot is tested for protein concentration via BCA assay and analyzed via SDS-PAGE to confirm the presence of sharp, clear bands as an indicator of quality. Product Details: Species:Mouse Antigen:tPA Format:Tissue Lysate Storage Conditions:-70 C This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies. Mouse Model Details Strain:C57BL6\/SJL Chromosome:8 Gene:PLAT Genomic TargetExon 4 Mutation:16 base pair deletion Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA. 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