Human ACE-2 Recombinant Protein His TagIHUACE2RHIS100UG
Human ACE-2 Recombinant Protein His Tag from Innovative Research has been recombinantly produced in HEK293 cells. This is a Liquid protein buffered in 20mM Tris, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4. with a purity of >95% as determined by reducing SDS-PAGE..
- Species: Human
- Target: ACE2
- Purity: >95% as determined by reducing SDS-PAGE.
- Source: HEK293 cells
- Storage Conditions: Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family which includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, heart, colon, small intestine and ovary at moderate levels. ACE2 is not inhibited by the classical ACE inhibitors, captopril and lisinopril and may play an important role in regulating the heart function.
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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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