Product References — Single Donor Human Red Blood Cells

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   LIPID NANOPARTICLES FOR DELIVERY OF BIOACTIVE MOLECULES Mina Ordobadi University of British Columbia November 2019 “…Nanoparticle drug delivery vehicles can be used for in vivo delivery of a variety of bioactive molecules including nucleic acid polymers and small molecule drugs for applications ranging from gene therapy to improving the efficacy of anticancer drugs… Human erythrocytes (RBC) (Innovative Research, Novi, MI) were rinsed with 0.9% saline before use…”   Related products available from Innovative Research also include: Single Donor Human Red Blood Cells Single Donor...

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   Cathelicidin Peptides Restrict Bacterial Growth via Membrane Perturbation and Induction of Reactive Oxygen Species Dean A. Rowe-Magnus, Adenine Y. Kao, Antonio Cembellin Prieto, Meng Pu, Cheng Kao American Society for Microbiology 10 September 2019 ”… All metazoans produce antimicrobial peptides (AMPs) that have both broad antimicrobial and immunomodulatory activity. Cathelicidins are AMPs that preferentially kill Gram-negative bacteria in vitro, purportedly by assembling into higher-order structures that perforate the membrane. We utilized high-resolution, single-cell fluorescence microscopy to examine their mechanism of action in real time....

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K Sven-Ulrik Gorr, Craig M. Flory, Robert J. Schumacher PLOS ONE May 9, 2019 “…Traditional antibiotics are losing their effectiveness due to increasing bacterial resistance. Combined with a decreasing pipeline of novel drugs, it is feared that many critical infections will be difficult or impossible to treat in the near future. …Human red blood cells (RBC) (single donor) were obtained from Innovative Research (Novi, MI)…”   Related products available from Innovative Research also...

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species Zee-Won Lee, Byoung Sik Kim, Kyung Ku Jang, Ye-Ji Bang, Suhyeon Kim, Nam-Chul Ha, Young Hyun Jung, Hyun Jik Lee, Ho Jae Han, Jong-Seo Kim, Jeesoo Kim, Pramod K. Sahu, Lak Shin Jeong, Myung Hee Kim, Sang Ho Choi Scientific Reports 13 March 2019 “…Increasing antibiotic resistance has led to the development of new strategies to combat bacterial infection…An aliquot of the supernatants was mixed with an equal volume of human erythrocytes (10% in PBS;...

Human Red Blood Cells from Innovative Research were used in the following study:   Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency Joseph S. Brown, Zeinab J. Mohamed, Christine M. Artim, Dana N. Thornlow, Joseph F. Hassler, Vincent P. Rigoglioso, Susan Daniel & Christopher A. Alabi Communications Biology volume 1, Article number: 220 (2018) "... This work has focused on the development of new experimental parameters for membrane-targeting antimicrobials, outside of the known properties of cationic charge and hydrophobicity. OligoTEAs have enabled the synthesis of isoamphipathic oligomers to specifically probe additional parameters in membrane disruption....