Fetal bovine serum (FBS) is a sterile, light brown colored liquid separated from the blood of the bovine fetus. All material meets with the approval of the U.S. Department of Agriculture and is obtained from sources free of BSE, Foot and Mouth Disease, and other reportable diseases pertaining to the species. Fetal bovine serum contains many substances which are needed by cultured cells to grow and live properly. It is the most widely used serum in the culturing of cells, tissues and organs in vitro, and is used in the manufacture of vaccines.