Innovative Research, Inc - "The researcher's source for biomedical products".

Human Fibronectin

Mr: 500 kDa

Synthesis: liver

Plasma concentration: 350 ng/ml

Human fibronectin is an adhesive glycoprotein found in the extracellular matrix and in plasma (1). Fibronectin is composed of two nearly identical polypeptide chains linked by a pair of disulfide bonds. Each subunit is organized into a variety of structural domains containing specific binding sites for cells, collagen, fibrin and glycosaminoglycans. Fibronectin also participates in complex interactions with other macromolecules to influence cellular properties including adhesion, morphology, migration, hemostasis and oncogenic transformation. The human fibronectin provided is suitable to promote the adhesion and propagation of cells in vitro when used to coat cell culture surfaces, including plasticware, glassware and microcarrier beads.

Technical Info

Innovative Research Inc. fibronectin is purified from human plasma and is provided in physiological buffer where it is stable at -20°C for up to one year. Repeated freeze/thaw cycles should be avoided. Protein concentration is determined spectrophotometrically at 280 nm using an extinction coefficient of 1.3 (0.1%). The purity is greater than 95% as determined by SDS-PAGE.

References

1. Moser, T.L. et al. (1993) J. Biol. Chem. 268:18917-18923.

IHFBN - Human fibronectin

Prepared from fresh human plasma. Ideal reagent for tissue culture studies and protein-protein interactions.

1.0 mg - $195
10 mg - $1,250

IMFBN - Mouse fibronectin

Prepared from fresh mouseplasma. Ideal reagent for tissue culture studies and protein-protein interactions.

1.0 mg - $400
10 mg - $1,995

IHMFBN - Hamster fibronectin

Prepared from fresh hamster plasma. Ideal reagent for tissue culture studies and protein-protein interactions.

1.0 mg - $195
10 mg - $1,250

46430 Peary Court
Novi, MI 48377

Phone: (248) 896-0145 Fax: (248) 896-0148