Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells

Mouse IgG ELISA Kit from Innovative Research was used in the following study:

Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells

Sonya J. Wolf, Shannon N. Estadta, Jonathan Therosa, Tyson Moorea, Jason Ellisb ,Jianhua Liua, Tamra J. Reeda, Chaim O. Jacobe, Johann E. Gudjonssond, J. Michelle Kahlenberga

Journal of Autoimmunity
2019 Jun 24

“…Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients experience devastating organ damage mediated by immune cells and inflammatory cytokine production [1,2]. Minimal sun exposure, especially ultraviolet (UV) B wavelengths, is a prominent factor that drives cutaneous inflammation in lupus patients. …Serum was collected 2 weeks post UVB treatment. Anti-IgG and dsDNA IgG antibody levels were analyzed via ELISA kits (Alpha Diagnostic, San Antonio, TX, and Innovative Research, Novi, MI)…”

Related products available from Innovative Research also include:

• Mouse IgG ELISA Kit
• Innovative Grade US Origin Mouse Balb C Plasma
• Mouse Balb C Serum