Product References — Single Donor Human Plasma Whole Blood Derived

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   An miRNA Fingerprint Using Neural-Enriched Extracellular Vesicles from Blood Plasma: Towards a Biomarker for Amyotrophic Lateral Sclerosis/Motor Neuron Disease Sandra Anne Banack, Rachael Anne Dunlop and Paul Alan Cox The Royal Society Publishing May 22, 2020 Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) continue to provide challenges for diagnosis since validated diagnostic biomarkers are currently unavailable. Rapid diagnosis and intervention in the disease process could be beneficial in slowing neurodegenerative disease progression as well...

Single Donor Human Plasma (Blood Derived) and Innovative Grade US Origin Rat Sprague Dawley Single Donor Plasma from Innovative Research was used in the following study:   Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma Snehal K Shukla, Hossam Kadry, Jayshil A Bhatt, Rasha Elbatanony, Fakhrul Ahsan & Vivek Gupta Future Science 13 Feb 2020 “A high throughput ultra-performance liquid chromatography (UPLC)-ultraviolet method for quantification of nintedanib in rat and human plasma was developed and optimized using chemometrical approach… Rat plasma and human plasma were acquired from Innovative...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction Amanda M. G. Lobo Igor R. S. Magalhães SSC plus 12/12/2019 “Tafenoquine, a synthetic analogue of primaquine, is a promising agent for the treatment of human malaria since this drug shows better antimalarial activity than primaquine in vitro and short treatment course. There are some methods for the quantification of tafenoquine in plasma, but none uses dispersive-liquid-liquid microextraction, an extraction technique that shows some advantages, such as miniaturization, low cost and high potential for...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry J.J.M Rood, M.J.van Haren, J.H.Beijnen, R.W.Sparidans Journal of Pharmaceutical and Biomedical Analysis January 2020 “…Osimertinib is a “third-generation’’ oral, irreversible, tyrosine kinase inhibitor. It is used in the treatment of non-small cellular lung carcinoma and spares wild-type EGFR. Due to its reactive nature, osimertinib is, in addition to oxidative routes, metabolized through GSH coupling and subsequent further metabolism of these conjugates. The extent of the non-oxidative metabolism...

Single Donor Human Serum Off The Clot, Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities Dmytro S. Kulyk, Devin J. Swiner, Taghi Sahraeian, and Abraham K. Badu-Tawiah Analytical Chemistry August 26, 2019 “Accurate and rapid analysis of complex microsamples are challenging tasks in translational research. Nanoelectrospray ionization (nESI) is the method of choice for analyzing small sample volumes by mass spectrometry (MS), but this technique works well only for polar analytes. Herein, we...