Product References — Innovative Grade US Origin Rat Sprague Dawley Plasma

Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Posted by Leanne Kodsmann on

Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Mouse CD1 Plasma, Rat Plasma, and Pooled Human Plasma from Innovative Research were used in the following study:   Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound Lara Pes, Stephan David Koester, Johannes Pall Magnusson, Serghei Chercheja, Federico Medda, Khalid Abu Ajaj, Didier Rognan, Steffen Daum, Friederike Inga Nollmann, Javier Garcia Fernandez, Patricia Perez Galan, Heidi-Kristin Walter, Anna Warnecke, Felix Kratz Journal of Controlled Release Volume 296, 28 February 2019, Pages 81-92 "... AE-KetoSulf07 and AE-Ester-Sulf07 are novel acid-sensitive albumin-binding prodrugs demonstrating tumor regressions in all of the evaluated human tumor xenograft...

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Plasma ameliorates endothelial dysfunction in burn injury

Posted by Leanne Kodsman on

Sprague Dawley Rat Plasma from Innovative Research was recently used in the following study: Plasma ameliorates endothelial dysfunction in burn injuryMariana Vigiola Cruz MD, Bonnie C. Carney BS, Jenna N. Luker MD, Kyle W. Monger BS, Juan Sebastian Vazquez MD, Lauren T. Moffatt PhD, Laura S. Johnson MD, Jeffrey W. Shupp MD Journal of Surgical Research, January 2019 " ... Sprague-Dawley rats were used to create small, medium, and large burns and uninjured controls. Three different intravenous resuscitation protocols were applied within each group: Lactated Ringer's (LR) alone, LR plus fresh frozen plasma (FFP), or LR plus albumin... In the...

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Simultaneous measurement of folate cycle intermediates in different biological matrices using liquid chromatography-tandem mass spectrometry

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Rat Plasma from Innovative Research was recently used in the following study: Simultaneous measurement of folate cycle intermediates in different biological matrices using liquid chromatography-tandem mass spectrometryJatin Nandania, Meri Kokkonen, Liliya Euro, Vidya Velagapudi Journal of Chromatography B: Volume 1092, 15 August 2018, Pages 168-178 ... Rat plasma with heparin as the anticoagulant was purchased from Innovative Research Laboratory (Novi, MI, USA). Whole Human Whole Blood was procured from the ... Related products available from Innovative Research also include: Innovative Grade US Origin Sprague Dawley Rat Plasma Innovative Grade US Origin Wistar Rat Plasma Rat Latent PAI-1 Depleted Plasma, Sodium...

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Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether

Posted by Leanne Kodsman on

Sprague Dawley Rat Plasma from Innovative Research was recently used in the following study: Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether Mai Gamal Elhennawy, Hai-ShuLin European Journal of Pharmaceutical Sciences, Vol. 118 (June 2018) ... study. Pooled Sprague-Dawley rat plasma was purchased from Innovative Research (Novi, MI, USA) and used as blank matrix when preparing the calibration standards and quality control samples. 2.2. LC"MS/MS analysis ...   Related products available from Innovative Research also include: Innovative Grade US Origin Sprague Dawley Rat Plasma Innovative Grade US Origin Sprague Dawley Rat Serum All Sprague Dawley Products

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Dihydroergotamine mesylate loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy

Posted by Leanne Kodsman on

Innovative Research's Rat Plasma was recently used in the following study: Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapyC Tas, JC Joyce, HX Nguyen, P Eangoor, JS Knaack… - Journal of Controlled …, 2017... DHE calibrants of concentrations 0.5, 1, 5, 10, 50, 100 and 200 ng/mL, and quality controls of concentrations 2 ng/mL and 150 ng/mL, were made in rat plasma (Sprague Dawley Rat Plasma, Innovative Research, Novi, MI, USA) . ...

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