Product References — Human Whole Blood

Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry

Posted by Corey Marcath on

Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry

Single Donor Human Whole Blood from Innovative Research was used in the following study:   Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry Devin J. Swiner, Sierra Jackson, George R. Durisek III, Bridget K. Walsh, Yaman Kouatli, Abraham K. Badu-Tawiah Analytica Chimica Acta 15 November 2019 “…Storage and quantitative analysis of small volumes of biofluids are challenging, especially when low concentrations of analytes are to be detected in the presence of complex matrices. In this study, we describe an integrated thread-based approach for stabilizing small blood volumes in the dry-state at room temperature, while also...

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Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry

Posted by Corey Marcath on

Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry

Single Donor Human Whole Blood from Innovative Research was used in the following study:   Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry Hyung MinKim, Ju-Hwan Park, Nguyen Phuoc Long, Dae-Duk Kim, Sung Won Kwon Journal of Food and Drug Analysis October 2019 “…A dried blood spot (DBS) sampling method was exploited to extract cardiovascular drugs using a small volume of whole blood of human and rodent. Thereafter, an analytical method using liquid chromatography with tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of 12 cardiovascular drugs. …Human whole blood with...

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In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K

Posted by Corey Marcath on

In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K Sven-Ulrik Gorr, Craig M. Flory, Robert J. Schumacher PLOS ONE May 9, 2019 “…Traditional antibiotics are losing their effectiveness due to increasing bacterial resistance. Combined with a decreasing pipeline of novel drugs, it is feared that many critical infections will be difficult or impossible to treat in the near future. …Human red blood cells (RBC) (single donor) were obtained from Innovative Research (Novi, MI)…”   Related products available from Innovative Research also...

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Alterations in phospholipid profiles of erythrocytes deep-frozen without cryoprotectants

Posted by Corey Marcath on

Alterations in phospholipid profiles of erythrocytes deep-frozen without cryoprotectants

Single Donor Human Whole Blood from Innovative Research was used in the following study:   Alterations in phospholipid profiles of erythrocytes deep-frozen without cryoprotectants Cho Y, Woo JH, Kwon OS, Yoon SS, Son J Drug Testing and Analysis 2019 Aug;11 “The erythrocyte membrane is composed of a phospholipid bilayer, which is known to undergo physicochemical changes during storage at low temperatures. This study was conducted to identify marker phospholipids that indicate alteration during deep-frozen storage and to determine the amount of marker phospholipids. …Single donor human whole blood was purchased from Innovative Research (Novi, MI, USA)…”   Related products available...

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Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer

Posted by Corey Marcath on

Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer

Single Donor Human Whole Blood from Innovative Research was used in the following study:   Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer Jungwhoi Lee, Jungsul Lee, Jae-Hoon Kim Cancer Letters 1 March 2019 “…Pancreatic cancer remains one of the most dangerous cancers with a grave prognosis. We have reported that dual specificity phosphatise 28 (DUSP28) could be secreted in pancreatic cancer cells. . …To measure scattered DUSP28 in whole blood of pancreatic cancer patients, blood samples (ten from pancreatic cancer patients and sixteen from healthy individuals) were...

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